| Managing the biopesticide when it is inserted in 
              the plant The bacterium 
              Bacillus thuringiensis (Bt) occurs naturally in soil. Insecticidal 
              strains, discovered in 1911, have been used for pest control since 
              the 1950s. Helicoverpa 
              moths are the main pests of cotton and, in the 1990s, INGARD ® 
              cottons containing a Bt protein toxic to them were released, resulting 
              in a substantial reduction in insecticide use where they are grown. 
              From season 2003/04, Australian growers will be able to plant BOLLGARD 
              II®, containing two Bt proteins. INGARD ® 
              plantings have led to a substantial reduction in the use of insecticides 
              on cotton but research doesn't end with the commercial release of 
              the GM cottons. Much effort goes on in the field and the lab in 
              the battle to prevent Helicoverpa developing resistance and 
              on assessing how effective these cotton varieties are across seasons 
              and in different conditions. And the search for additional toxic 
              proteins continues. For INGARD ®, 
              refuge crops are grown to provide a source of susceptible moths 
              to mate with Bt survivors, thereby diluting any resistance genes. 
              In BOLLGARD II®, it is hoped that the presence of two toxic 
              proteins which act differently will considerably slow the development 
              of any resistance. Supported by: Australian Cotton Cooperative Research Centre,
 Cotton Research and Development Corporation
 
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